Chief Physician, Doctoral Supervisor. Director of the Department of Endocrinology and Metabolism, Deputy Director of the Department of Medical Genetics, and Director of the Clinical Research Ward
Affiliated HospitalShanghai Children's Medical Center (National Children's Medical Center), affiliated with Shanghai Jiao Tong University School of Medicine
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He has presided over and participated in multiple research projects, including the "Eleventh Five-Year Plan" National Science and Technology Support Project and the National Natural Science Foundation of China, and has published over 130 papers. He led the world's first in vivo base-editing drug clinical study for childhood and adolescent hyperchylomicronemia (FCS), exploring in vivo gene-editing therapy through LNP delivery technology; he also led the world's first gene therapy project for childhood and adolescent Gaucher disease, selected as one of the seven major advances in pediatrics in 2024. His expertise includes short stature, precocious puberty, obesity-related syndromes, special types of diabetes, Gaucher disease, hyperchylomicronemia, and rare inherited metabolic diseases.