Chief Physician, Professor, Doctoral Supervisor, Distinguished Professor of Shanghai Jiao Tong University
Affiliated HospitalRenji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
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Distinguished Honorary Professor at the Australian National University, Director of the Sino-Australian Joint Research Center for Personalized Immunology. Research Areas : Molecular genetic mechanisms and targeted therapy research of autoimmune diseases such as systemic lupus erythematosus (SLE). Cutting-Edge Technologies: Pioneered the discovery that abnormal activation of the type I interferon pathway is a major molecular phenotype of lupus, and established a novel biomarker analysis system for clinical subgroup classification and efficacy evaluation of lupus; in 2024, he revealed for the first time in *Science* the mechanism by which ZEB2 drives the formation of pathogenic B cells in lupus. Areas of Expertise: SLE, dermatomyositis, gout, rheumatic heart disease, and other complex rheumatic diseases. Academic Highlights: Chief Scientist of the 973 Program, National Outstanding Young Scientist, and Leading Talent of the National "Ten Thousand Talents Program"; published over 100 papers in journals such as *Cell*, *Nature Genetics*, *Nature Medicine*, *Immunity*, and *Science*; served as Associate Editor of the internationally authoritative SLE textbook *DUBOIS' Lupus Erythematosus*, and received the Edmund Dubois Memorial Award from the American College of Rheumatology.