Medical Care in China

Mitral regurgitation
Treatment in China

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Internal-surgical collaboration‌Comprehensive selection of medical, surgical, and interventional treatments.
Complex heart diseasescover coronary artery disease, valvular heart disease, and structural heart disease.
Major vessel diagnosis and treatmentinvolves professional assessment of diseases of the aorta and other major blood vessels.
Severe Illness Treatment SupportPossesses comprehensive treatment capabilities for cardiovascular critical illnesses.

Condition Guide

About Mitral regurgitation

Understand the condition, common triggers and treatment options that may require specialist assessment.

Disease Introduction

Mitral regurgitation is an incomplete closure of the "valve" between the left atrium and left ventricle, causing blood to flow back into the atrium during cardiac contraction. Early symptoms may be asymptomatic, gradually progressing to shortness of breath on exertion, chest tightness, nocturnal awakenings with dyspnea, leg swelling, and fatigue. It is classified into primary (due to valvular disease itself) and secondary (due to cardiac enlargement or atrial fibrillation causing valvular annulus dilation). The general principle of treatment is to administer heart failure medications effectively for secondary mitral regurgitation, while for severe primary mitral regurgitation, early evaluation for repair or replacement is crucial to avoid further damage to cardiac function.

Cutting-edge high-precision diagnostic and treatment technologies

  1. Domestic mitral valve clips approved : Keke's transcatheter mitral valve repair system was approved by the NMPA in May 2025; Yingmai Medical and Shanghai Shenqi's transcatheter mitral valve clip systems were approved in March and April 2026, respectively, for surgically high-risk, anatomically appropriate degenerative regurgitation patients.
  2. Domestic production of edge-to-edge repair : The domestically produced transfemoral mitral valve edge-to-edge repair system DragonFly has been approved for marketing. The DRAGONFLY-DMR study showed good efficacy and safety in 120 high-risk patients with moderate to severe mitral regurgitation.
  3. Advancement of surgical timing according to guidelines : The 2025 ESC/EACTS Valve Guidelines recommend surgical mitral valve repair for patients with low-risk, asymptomatic, severe primary regurgitation who meet at least three of the following criteria: atrial fibrillation, resting pulmonary artery systolic blood pressure greater than 50 mmHg, left atrial enlargement, and moderate to severe secondary tricuspid regurgitation.
  4. Classification of secondary regurgitation : The 2025 guidelines for the first time clearly state that for atrial secondary regurgitation, mitral valve surgery combined with atrial fibrillation ablation and left atrial appendage occlusion can be performed on the basis of optimal drug therapy. For those who are not suitable for surgery, TEER can be considered. The indications for TEER for ventricular secondary regurgitation have been strengthened.
  5. Minimally invasive surgery gains recognition : The 2025 guidelines clearly state that minimally invasive mitral valve surgery can be considered in experienced centers to shorten hospital stays, accelerate recovery, and provide a surgical repair pathway for those who are unwilling or unsuitable for open-heart surgery.
 

Care Overview

Mitral regurgitation Treatment in China

The medical team will develop a personalized protocol based on the pathology type, stage, genetic test, previous treatment history, and the patient's physical condition.

Leading Specialists

Trusted Expertise Across Leading Specialties

He Yong

Deputy Director of Cardiology, Head of Coronary Artery Disease Group, Chief Physician

Cardio-Cerebrovascular

Research areas : interventional treatment of complex and high-risk coronary arteries; intravascular coronary imaging (IVUS); chronic occlusive disease (CTO). Cutting-edge technologies: The first complex high-risk PCI in China supported by a domestically produced transcatheter left ventricular pump assist device; the first in Southwest China to carry out complex coronary interventions and high-speed rotational atherectomy under intravascular ultrasound guidance; CTO retrograde interventional treatment and

West China Hospital of Sichuan University logo Affiliated Hospital West China Hospital of Sichuan University
Fu Hua

Chief Physician, Doctoral Supervisor | Head of the Arrhythmia Subspecialty Group

Cardio-Cerebrovascular

Research areas: atrial fibrillation, ventricular arrhythmias, complex tachyarrhythmias; Cutting-edge technologies: 3D mapping radiofrequency ablation, pulsed electric field ablation, one-stop surgery for atrial fibrillation (ablation + left atrial appendage occlusion); Academic Highlights: Deputy Head of the Left Atrial Appendage Occlusion Group of the Chinese Society of Cardiac Electrophysiology and Pacing; specializes in ablation of ventricular tachycardia in organic heart disease, has presided over mul

West China Hospital of Sichuan University logo Affiliated Hospital West China Hospital of Sichuan University
Song Lei

Deputy Director of the Coronary Artery Disease Center, specializing in intravascular imaging and QFR

Cardio-Cerebrovascular

Research areas: Coronary artery disease and complex coronary interventional treatment, intravascular imaging and physiology of the coronary arteries. Cutting-edge technology: Co-first author of the FAVOR III China study published in *The Lancet* (impact factor 207), confirming that QFR-guided coronary intervention can significantly improve prognosis. Invited by *The Lancet* as the sole author from China to participate in writing a major global report on "Ischemic Heart Disease". Drafted the National Healt

Fuwai Hospital, Chinese Academy of Medical Sciences logo Affiliated Hospital Fuwai Hospital, Chinese Academy of Medical Sciences
Angie

Professor, Doctoral Supervisor, Department Head

Cardio-Cerebrovascular

- Research areas: Congenital heart disease surgery, heart transplantation, end-stage heart failure surgery; - Core technologies: Complex congenital heart disease correction in infants and young children, heart transplantation; - Areas of expertise: Various complex congenital heart diseases, dilated cardiomyopathy, and end-stage heart failure; - Academic Value: President of the Cardiovascular Surgery Branch of the Sichuan Provincial Medical Association, Standing Committee Member of the Congenital Heart Dis

West China Hospital of Sichuan University logo Affiliated Hospital West China Hospital of Sichuan University
Wu Zhong

Professor, Doctoral Supervisor, Deputy Director of Department (Academic Leader of the Coronary Artery Surgery and Chronic Pulmonary Embolism Surgery Subspecialty)

Cardio-Cerebrovascular

- Research areas: aortic disease, chronic thromboembolic pulmonary hypertension; coronary artery bypass grafting for coronary heart disease; surgical treatment of chronic thromboembolic pulmonary hypertension (CTEPH); valvular heart disease, aortic aneurysm, chronic atrial fibrillation. - Core technologies: Sun's procedure for aortic dissection, coronary artery bypass grafting; pulmonary endarterectomy (PEA) - first to be routinely performed in Southwest China, filling the technological gap in West China

West China Hospital of Sichuan University logo Affiliated Hospital West China Hospital of Sichuan University
Sun Xiaogang

Aortic Surgery and Neuroprotection

Cardio-Cerebrovascular

Research areas: Surgical clinical and basic research on aortic diseases, with a focus on treatment systems for the root of type A aortic dissection, repair strategies for bicuspid aortic valve malformation, and new paradigms for the treatment of the neurological system in aortic arch surgery. Cutting-edge technology: In 2017, the institute pioneered the application of aortic balloon occlusion technology to total aortic arch replacement and stent elephant trunk surgery, shortening the deep hypothermic circ

Fuwai Hospital, Chinese Academy of Medical Sciences logo Affiliated Hospital Fuwai Hospital, Chinese Academy of Medical Sciences

Patient Stories

See the Next Step Through Patient Journeys

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Patient records Name: David Chen Age: 52 Nationality: Vietnamese Diagnosis: Acute Stanford type A aortic dissection (DeBakey type I, involving the ascending aorta, aortic arch, and descending aorta, complicated by severe aortic regurgitation) Treatment Hospital: Fuwai Hospital, Chinese Academy of Medical Sciences (National Center for Cardiovascular Diseases) — Vascular Surgery Center David now jogs 5 kilometers along the Vancouver beach every morning. He says that with each heartbeat, he feels grateful t

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