Key Department Guide

Proton / Heavy Ion Therapy Center

Proton and heavy ion therapy is a type of particle radiotherapy that utilizes physical properties such as the Bragg peak to reduce the radiation dose to normal tissues in certain tumors. It is commonly used for pediatric tumors, skull base tumors, eye tumors, some central nervous system tumors, head and neck tumors, prostate cancer, liver cancer, and in re-radiotherapy settings. For patients with specific anatomical locations or those requiring reduced long-term toxicity, particle therapy may reduce the dose to the heart, lungs, digestive tract, and gonads, but indications must be strictly adhered to. Pre-treatment procedures require pathological confirmation, staging assessment, target delineation, and treatment planning, as well as evaluation of respiratory movement, metal implants, and organ movement effects. Current evidence suggests that it can reduce some toxicity in certain tumors, but overall survival benefits still depend on tumor type and stage, and high-quality randomized evidence is limited. Cost, accessibility, and long-term outcomes remain important considerations.

Hospital Rankings

Hospitals Specializing in Proton / Heavy Ion Therapy Center

The following hospitals provide relevant clinical capabilities in this department. Rankings are for care-planning reference only.

4 Hospitals
NO.01 Wuwei · Partner Hospital

Wuwei Cancer Hospital, Gansu Province

Oncology

The hospital is a Grade III Class A oncology hospital designated by the National Health Commission. It is the first hospital in China to clinically apply a heavy ion therapy system and the only hospital in the world operating two heavy ion cancer treatment systems. It ranks 7th nationwide among tumor particle (proton/heavy ion) therapy centers. The hospital manages and operates two heavy ion therapy systems with independent intellectual property rights in China: the Wuwei Heavy Ion Center and the Lanzhou Heavy Ion Center. It is a world-first hospital in several pioneering technologies, including completing treatment within one day with a single fractionation, precision heavy ion therapy under ventilator control, and bladder cancer treatment with precise bladder capacity control.

NO.02 Shanghai · Partner Hospital

Shanghai Proton and Heavy Ion Hospital

Oncology

The hospital is the first medical institution in China and the third globally to possess both proton and heavy ion dual-particle radiotherapy platforms. It is a national hub for the clinical translation of particle radiotherapy technology and a national referral center for particle radiotherapy of localized solid tumors and tumors recurring after photon radiotherapy. The Radiotherapy Center is affiliated with the Shanghai Clinical Medical Research Center for Radiotherapy, the Shanghai Cancer Radiotherapy Research Center, and the Radiotherapy Quality Control Center. It is the first member unit in China of the Radiotherapy Toxicology Group (RTOG) and benchmarks itself against the Heidelberg Heavy Ion Center in Germany, the National Institute of Radiation Medicine in Japan, and the Proton Therapy Center at Massachusetts General Hospital in the United States.

NO.03 Guangzhou · Partner Hospital

Sun Yat-sen University Cancer Center

Oncology

The center's oncology department is a national key discipline, housing the National Key Laboratory for Prevention and Treatment of Malignant Tumors in South China, a key laboratory of the Ministry of Education, and the National Clinical Trial Research Center for New Drugs (Anti-tumor Drugs). It is also the supporting unit for the Guangdong Provincial Cancer Center and the Guangdong Provincial Esophageal Cancer Institute. Its scientific and technological influence ranked first in the 2023 China Hospital Science and Technology Value Ranking for Oncology, and its comprehensive strength in oncology as a specialty consistently ranks among the top two in China according to the Fudan University China Hospital Ranking. In the 2024 Nature Index ranking, it ranked fifth among global cancer centers. The center boasts 3 academicians of the Chinese Academy of Sciences, 3 academicians of the Chinese Academy of Engineering, and 47 national-level talents.

NO.04 Shanghai · Partner Hospital

Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

OncologyHematologyGastroenterologyUrologyInternal MedicineSurgeryOrthopedics

Ruijin Hospital consistently ranks among the top four hospitals in China according to the comprehensive hospital rankings released by the Fudan University Hospital Management Institute. It is a national medical center construction unit and possesses national-level platforms such as the National Clinical Research Center for Metabolic Diseases and the National Clinical Research Center for Hematological Diseases. The hospital currently has four key disciplines designated by the Ministry of Education (Hematology, Endocrinology and Metabolic Diseases, Cardiology, and Neurology), 22 national key clinical specialties, and one national key laboratory for medical genomics. The hospital has been awarded the title of National Civilized Unit four times consecutively and has received honors such as the National May 1st Labor Medal and the National Advanced Collective of the Health System. It is also a national demonstration unit for integrated traditional Chinese and Western medicine.