Medical Care in China

gastric stromal tumor
Treatment in China

Provide a clear and complete coordinated pathway from expert assessment to treatment and rehabilitation.

Get a Care Plan and Cost Estimate
Comprehensive coverage of digestive diseases, includinggastrointestinal, hepatobiliary, pancreatic, and anorectal diseases, all of which can be assessed.
Endoscopic precision diagnosis and treatmentis used for examination, biopsy and some minimally invasive treatments.
Complex digestive surgerycovers gastrointestinal tumors, intestinal obstruction, and complex abdominal diseases.
Multidisciplinarycollaborative assessment involving internal medicine, surgery, imaging, and oncology teams.

Condition Guide

About gastric stromal tumor

Understand the condition, common triggers and treatment options that may require specialist assessment.

Disease Introduction

Gastrointestinal stromal tumors (GISTs) are a type of tumor that grows in the muscular layer of the stomach wall. They are not the same as ordinary stomach cancer. Most are caused by mutations in the KIT or PDGFRA genes. In the early stages, they are often asymptomatic, but as they grow, they may become palpable as a mass in the abdomen, causing bleeding or anemia. They are particularly "sensitive" to targeted drugs: oral imatinib can often significantly shrink large tumors, and when combined with laparoscopic minimally invasive surgery, many patients can have the tumors completely removed without major surgery. Even in advanced stages, there are still a series of treatment options such as sunitinib and retinotinib, and some new drugs have been included in medical insurance.

Cutting-edge high-precision diagnostic and treatment technologies

  1. First-line targeted therapy : Imatinib (Gleevec) is a first-line targeted therapy for unresectable or metastatic GIST. Preoperative use can significantly shrink large tumors before surgical resection.
  2. Second-line sunitinib : For patients who have progressed or developed resistance to imatinib, sunitinib (Sutent) is the standard second-line treatment recommended by domestic and international guidelines.
  3. Fourth-line ripretinib : Ripetinib was approved in China in March 2021 and is the first fourth-line treatment for advanced GIST in China. It is used for adult patients who have previously received three or more kinase inhibitors, including imatinib.
  4. Genotyping-guided medication : Approximately 80% of GISTs are caused by KIT gene mutations and approximately 5% by PDGFRA gene mutations (totaling approximately 85% of GISTs); PDGFRA exon 18 (including D842V) mutations are not sensitive to imatinib, and avapritinib is its precise targeted therapy.
  5. Preoperative targeted tumor shrinkage : For giant gastric GISTs or those that are difficult to resect at R0, oral imatinib is administered for about six months to shrink the tumor, followed by total laparoscopic wedge resection of the stomach, which can preserve normal gastric tissue and spleen.

Care Overview

gastric stromal tumor Treatment in China

The medical team will develop a personalized protocol based on the pathology type, stage, genetic test, previous treatment history, and the patient's physical condition.

Leading Specialists

Trusted Expertise Across Leading Specialties

Li Jingnan

Professor , specializing in colorectal cancer screening and neuroendocrine tumors

Gastroenterology

Research areas: carcinogenesis mechanisms, clinical screening and prevention of colon polyps and colorectal cancer; neuroendocrine tumors of the gastrointestinal pancreas. Cutting-edge technology: Long-term research on the treatment of colon polyps and the screening, prevention, and carcinogenesis mechanisms of colorectal cancer (Visiting Scholar at Massachusetts General Hospital, Harvard Medical School). Led the compilation of national expert consensus on neuroendocrine tumors and gastrointestinal mucosa

Peking Union Medical College Hospital, Chinese Academy of Medical Sciences logo Affiliated Hospital Peking Union Medical College Hospital, Chinese Academy of Medical Sciences
Ni Quanxing

Chief Physician, Professor, Founder of the Discipline

Gastroenterology

Research areas : Basic and clinical research on pancreatic tumors, comprehensive treatment of advanced pancreatic cancer; Cutting-edge technology: Establishment of a multidisciplinary diagnosis and treatment system for pancreatic cancer; Areas of expertise: Pancreatic cancer, ampullary cancer, and tumors at the bile duct-pancreatic junction; Academic highlights: A leading authority on pancreatic tumors in China, and Director of the Academic Committee of the Shanghai Pancreatic Tumor Institute; Core values

Fudan University Cancer Hospital logo Affiliated Hospital Fudan University Cancer Hospital
Ji Ming

Professor – Specializing in Interventional Digestive Endoscopy

Gastroenterology

Research areas: Endoscopic interventional (minimally invasive) diagnosis and treatment of digestive diseases, including endoscopic diagnosis and treatment of early gastrointestinal cancers, pancreatic and biliary diseases, and gastrointestinal bleeding. Cutting-edge technology: Proficient in interventional (minimally invasive) endoscopic diagnosis and treatment of digestive tract cancers, with extensive experience in endoscopic treatment of early gastrointestinal cancers and pancreatic and biliary disease

Beijing Friendship Hospital (Second Clinical Medical College), Capital Medical University logo Affiliated Hospital Beijing Friendship Hospital (Second Clinical Medical College), Capital Medical University
Wu Bin

Specializing in Colorectal Tumor Surgery and Inflammatory Bowel Disease

Gastroenterology

Research areas: Surgical treatment of colorectal tumors and surgical treatment of inflammatory bowel disease. Cutting-edge technology: Participated in laparoscopic minimally invasive surgery for colorectal cancer and surgical treatment of inflammatory bowel disease in the professional group, and participated in multiple national multicenter clinical studies. Specializes in treating: colorectal cancer, inflammatory bowel disease (Crohn's disease, ulcerative colitis), and intestinal obstruction. Academic Hi

Peking Union Medical College Hospital, Chinese Academy of Medical Sciences logo Affiliated Hospital Peking Union Medical College Hospital, Chinese Academy of Medical Sciences
Li Peng

Chief Physician, Professor, Director of the Digestive Center

Gastroenterology

Research areas : early gastrointestinal cancer, endoscopic ultrasound (EUS), pancreatic and biliary diseases; Cutting-edge technology: EUS for precise diagnosis of pancreatic tumors and intramural lesions of the gastrointestinal tract; Areas of expertise: early esophageal/gastric cancer, pancreatic lesions, common bile duct stones; Academic highlights: Dean of the School of Digestive Health, Capital Medical University; Core value: Establishing standardized clinical pathways for early gastrointestinal canc

Beijing Friendship Hospital (Second Clinical Medical College), Capital Medical University logo Affiliated Hospital Beijing Friendship Hospital (Second Clinical Medical College), Capital Medical University
Xu Jin

Chief Physician, Professor

Gastroenterology

Research Areas : Neoadjuvant conversion therapy for pancreatic cancer, peritoneal metastasis of pancreatic cancer; Cutting-edge Technology: Neoadjuvant therapy for pancreatic cancer + HIPEC (hyperthermic intraperitoneal perfusion) combined regimen; Areas of Expertise: Locally advanced pancreatic cancer, peritoneal metastasis of pancreatic cancer, periampullary cancer; Academic Highlights: Key expert in pancreatic cancer conversion therapy; Core Value: Improved screening criteria for conversion surgery in

Fudan University Cancer Hospital logo Affiliated Hospital Fudan University Cancer Hospital

Patient Stories

See the Next Step Through Patient Journeys

Giant Pancreatic Pseudocyst : A Hidden Danger After an CASE 01
PATIENT JOURNEY

Giant Pancreatic Pseudocyst : A Hidden Danger After an "Emergency" - How a Russian Patient Dissolved a Fluid-Filled Sac in His Abdomen Using "Scarless" Endoscopic Techniques in China

Gastroenterology

Patient records Name: Elena Age: 62 years old Nationality: Russian Diagnosis: Recovery phase of severe acute pancreatitis, giant pancreatic pseudocyst (15cm in diameter). Treatment hospital: Department of Pancreatic Surgery, West China Hospital, Sichuan University. After surviving the life-or-death ordeal of acute pancreatitis, some patients face a troublesome sequela — pancreatic pseudocysts. This fluid-filled "sac" is like a time bomb, potentially causing infection, rupture, or compression of surroundi

View case details →
Chronic Pancreatitis : A German Engineer's Journey to Pain Relief - How We Helped Him End Years of Severe Pain Using Endoscopic Techniques CASE 02
PATIENT JOURNEY

Chronic Pancreatitis : A German Engineer's Journey to Pain Relief - How We Helped Him End Years of Severe Pain Using Endoscopic Techniques

Gastroenterology

Patient records Name: Hans Age: 52 years old Nationality: German Diagnosis: Chronic alcoholic pancreatitis, multiple pancreatic duct stones, dilation of the main pancreatic duct (diameter >1cm), and intractable abdominal pain. Treatment Hospital: Pancreatic Center, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine For patients with chronic pancreatitis, the recurring, deep-seated abdominal pain is an indescribable torment. Hans's story tells how he ended years of pain in China

View case details →
Crohn's Disease-Related Bowel Obstruction : How a British Patient Finds a CASE 03
PATIENT JOURNEY

Crohn's Disease-Related Bowel Obstruction : How a British Patient Finds a "Balance on a Knife's Edge" in China When "Green Cancer" Repeatedly Causes Obstruction

GastroenterologySurgery

Patient records Name: David Age: 35 Nationality: British Diagnosis: Crohn's disease (ileocolic type, stricture type), recurrent small bowel obstruction Treatment Hospital: Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Crohn's disease, known as the "green cancer," is incurable and recurrent, leading to serious complications such as intestinal stenosis, perforation, and fistulas. David's story tells how he found a precise balance between "over-operation" and "recurrent obstr

View case details →

Next Step

Get a Care Plan
and Cost Estimate.

Tell us about your diagnosis and needs, and our team will help screen the right hospital and explain the next steps.

Email:goldentcm@163.com

Get a Care Plan and Estimate

Once you submit your information, a member of our support team will reach out to you within one business day.