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Nasal polyps
Treatment in China

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Condition Guide

About Nasal polyps

Understand the condition, common triggers and treatment options that may require specialist assessment.

Disease Introduction

Nasal polyps are lychee-like growths formed by chronic inflammation and edema of the nasal or sinus mucosa. They often coexist with chronic sinusitis, medically termed chronic sinusitis with nasal polyps. Allergies, asthma, type 2 nasal inflammation, and recurrent respiratory infections are the main contributing factors. Typical symptoms include persistent nasal congestion, purulent nasal discharge, decreased or even lost sense of smell, and facial swelling and pain. Most patients can achieve good control with standardized medication and minimally invasive surgery. In recent years, targeted biological drugs have given hope for long-term relapse-free treatment for patients with refractory or recurrent conditions.

Cutting-edge high-precision diagnostic and treatment technologies

1. Anti-IL-4Rα biologics : Dupilumab and other anti-IL-4Rα monoclonal antibodies inhibit type 2 inflammation at its source by blocking IL-4 and IL-13 signaling, thereby reducing nasal polyps and improving nasal congestion and decreased sense of smell in the long term. They are used for adult chronic sinusitis with nasal polyps that are not well controlled by hormones or surgery, and can significantly reduce the use of systemic hormones and postoperative recurrence. The relevant indications in China are being expedited for approval.
2. New indications for anti-IL-5 monoclonal antibodies : Anti-IL-5 monoclonal antibodies such as mepolizumab target the eosinophilic inflammatory pathway and are used for type 2 inflammatory phenotype nasal polyps that are poorly controlled by hormones and/or surgery. They can reduce the dosage of oral hormones and reoperation, and have been included in the medical insurance catalog, significantly reducing the burden of long-term medication.
3. Domestically produced biologics included in medical insurance : Domestically produced targeted type 2 inflammatory biologics such as spritzibimab have been included in the national medical insurance catalog for patients with nasal polyps who do not respond well to hormones and/or surgery. They have good efficacy and safety, significantly improving treatment accessibility and reducing the long-term economic burden on patients.
4. Novel anti-IL-5 drug approved : A novel long-acting anti-IL-5 monoclonal antibody is approved as an adjunct to nasal corticosteroids for adult nasal polyps that are poorly controlled by systemic hormones and/or surgery. It allows for longer dosing intervals and better compliance, further enriching the options of biologics for patients with type 2 inflammatory phenotype.
5. Navigation-guided endoscopic minimally invasive surgery : Nasal endoscopic image navigation combined with a powered system precisely removes polyps, opens various sinuses, and simultaneously addresses septal deviation and bullous middle turbinate. Combined with postoperative maintenance with biological agents, this significantly reduces the long-term recurrence rate and is a core surgical treatment method. The extent of resection is individualized according to the size of the polyp and the sinus drainage situation, aiming to solve ventilation and drainage problems in a single surgery.

Care Overview

Nasal polyps Treatment in China

The medical team will develop a personalized protocol based on the pathology type, stage, genetic test, previous treatment history, and the patient's physical condition.

1. Standard drug treatment for mild cases : For those with initial onset and small polyps, standard treatment includes nasal corticosteroid spray, saline nasal irrigation and anti-allergy medication, and regular nasal endoscopy follow-up. Symptoms can be controlled in most cases. Postoperative follow-up is required to evaluate the efficacy and safety.
2. Moderate to severe endoscopic surgery : For patients with severe nasal congestion, large polyps, or combined sinus drainage obstruction, endoscopic sinus surgery is performed to remove polyps, open sinus ostia, restore nasal ventilation and drainage, and improve symptoms such as headache and runny nose. It also improves symptoms such as headache, runny nose, and decreased sense of smell.
3. Refractory and Relapsed Biological Targeted Therapy : For patients with type 2 inflammatory phenotype who experience repeated postoperative relapses, oral steroid dependence, or concurrent asthma, long-term maintenance therapy with biologics such as dupilumab and mepolizumab is recommended. This breaks the relapse cycle and reduces the need for further surgery.
4. Simultaneous treatment of upper and lower airways : For patients with concurrent allergic asthma, a single administration of biological agents can simultaneously control nasal polyps and lower airway inflammation, reducing the use of systemic hormones and achieving dual control with one drug, resulting in synergistic benefits. Postoperative follow-up examinations are required to assess efficacy and safety.
5. Phenotypic Precision Drug Selection : Combining blood eosinophil counts, total IgE, and nasal secretion markers to determine the type 2 inflammatory phenotype, guiding the selection of IL-4Rα, IL-5, or IL-5Rα targeted drugs to improve response rates.
6. Postoperative follow-up to prevent recurrence : After surgery, adhere to standardized nasal irrigation, local hormone nasal spray and regular nasal endoscopy cleaning, and timely follow-up visits. If necessary, add biological agents in the early stage to consolidate the curative effect, reduce the long-term recurrence of nasal polyps and improve the quality of life.

1. Anti-inflammatory at the root : Biological agents directly block the core pathway of type 2 inflammation, resulting in the shrinkage of polyps and long-term improvement of nasal congestion and decreased sense of smell, no longer relying solely on repeated oral hormones;
2. Reduce the need for reoperation : Standardized postoperative combined biological maintenance therapy can significantly reduce the probability of polyp recurrence and reoperation with endoscopic sinus surgery;
3. Minimally invasive and scarless facial surgery : The nasal endoscope is used to operate through the nostrils, leaving no incisions on the face. The hospital stay is short, recovery is fast, and it does not affect appearance.
4. Improved sense of smell and quality of life : After the polyps shrink, nasal ventilation and sense of smell gradually recover, and sleep, snoring and daytime mental state improve simultaneously;
5. Improved accessibility to medical insurance : Many biological agents have been approved in China and included in the medical insurance catalog, significantly reducing the economic burden of long-term treatment;
6. Personalized and precise treatment : Precise drug selection based on inflammatory phenotype and comorbidity avoids a one-size-fits-all approach and improves long-term control rate and medication safety.

Network of partner hospitals

Recommended Hospitals

Selected leading medical centers with strong specialties and international patient services.

Peking Union Medical College Hospital, Chinese Academy of Medical Sciences

Beijing · Partner Hospital

Peking Union Medical College Hospital, Chinese Academy of Medical Sciences

RehabilitationOrgan TransplantRare & Complex DiseasesOncologyGastroenterologyNeurologyUrologyInternal MedicineSurgeryHepatobiliaryOrthopedicsObstetrics & GynecologyENTCosmetic Surgery

In the ranking of Chinese hospitals released by the Fudan University Hospital Management Institute, Peking Union Medical College Hospital has topped the comprehensive ranking for more than ten consecutive years, and has twice ranked first in the national performance evaluation of tertiary public hospitals. Among the 42 specialties covered in the comprehensive specialty ranking, 28 of Peking Union Medical College Hospital's specialties are ranked in the top 10. Nine specialties, including pathology, rheumatology, obstetrics and gynecology, general surgery, neurology, nuclear medicine, emergency medicine, critical care medicine, and allergy, rank first in the country; several specialties, including radiology, anesthesiology, endocrinology, laboratory medicine, ultrasound medicine, and gastroenterology, rank second in the country. The hospital is a national center for the diagnosis and treatment of complex, critical, and rare diseases designated by the National Health Commission, a national demonstration base for higher medical education and standardized residency training, and a national core base for clinical medical research and technological innovation.

Year Founded: 1921
Beds: 3000

National Center for Stomatology, Peking University School of Stomatology

Beijing · Partner Hospital

National Center for Stomatology, Peking University School of Stomatology

ENT

As a "National Center for Stomatology," the hospital boasts a world-leading scale of stomatological medical services. It possesses all eight of the first batch of national key clinical specialty construction projects in stomatology, including Endodontics, Periodontology, Oral and Maxillofacial Surgery, Prosthodontics, Orthodontics, Pediatric Dentistry, Oral Mucosal Diseases, and Implant Dentistry. The hospital is the National Center for Quality Management and Control of Stomatological Medicine, entrusted by the National Health Commission. It is the only stomatological hospital in China selected for the pilot program of modern hospital management system. It was among the first stomatological medical institutions nationwide to pass the Level 5 certification for electronic medical records, the Level 4A certification for interoperability, and the ISO 15189 international clinical laboratory certification.

Year Founded: 1941
Beds: 363

Eye, Ear, Nose and Throat Hospital Affiliated to Fudan University (Shanghai ENT Hospital)

Shanghai · Partner Hospital

Eye, Ear, Nose and Throat Hospital Affiliated to Fudan University (Shanghai ENT Hospital)

ENT

The hospital's Department of Otolaryngology is a national key clinical specialty and a national quality control center for otolaryngology-head and neck surgery, consistently ranking first in the national specialty rankings for over ten years. The Department of Ophthalmology is a key discipline of the Ministry of Education and a national key clinical specialty, consistently ranking among the top three in China and first in East China in the ranking of best hospital specialties for over ten years. The hospital is one of the world's largest centers for the diagnosis, treatment, and research of otolaryngological-head and neck diseases.

Year Founded: 1952
Beds: 894

Shanghai Jiao Tong University School of Medicine Affiliated Sixth People's Hospital

Shanghai · Partner Hospital

Shanghai Jiao Tong University School of Medicine Affiliated Sixth People's Hospital

RehabilitationInternal MedicineOrthopedicsENT

The hospital is a national orthopedic medical center, with orthopedics and sports medicine being two national key clinical specialties. Orthopedics is a national key discipline, one of the first batch of national key clinical specialties designated by the Ministry of Health, the Shanghai Clinical Medical Center for Trauma Orthopedics, and a key construction unit in Shanghai. In the Fudan University's ranking of Chinese hospital specialty reputation, orthopedics has consistently ranked among the top two nationwide for many years, placing it in the first tier. In the comprehensive ranking of China's hospital science and technology (STEM) values, it ranks around 25th nationwide.

Year Founded: 1904
Beds: 2556

Shanghai Jiao Tong University School of Medicine Affiliated Ninth People's Hospital

Shanghai · Partner Hospital

Shanghai Jiao Tong University School of Medicine Affiliated Ninth People's Hospital

ENTCosmetic Surgery

The Ninth People's Hospital boasts three national key disciplines: Stomatology, Plastic and Reconstructive Surgery, and Orthopedics; nine national key clinical specialties; and four national "211 Project" key disciplines. It houses the National Clinical Research Center for Oral Diseases, and the National Stomatological Center (Shanghai) will officially be established there in 2026. In the Fudan University ranking of Chinese hospitals, its Plastic and Reconstructive Surgery department has consistently ranked first nationwide for many years, its Stomatology department third, and its Otolaryngology and Ophthalmology departments among the top. It is a member of the International Association of Oral and Maxillofacial Surgeons (IAOMS) and has multiple international training center designations.

Year Founded: 1920
Beds: 1820

Zhongshan Ophthalmic Center, Sun Yat-sen University

Guangzhou · Partner Hospital

Zhongshan Ophthalmic Center, Sun Yat-sen University

ENT

The center is the only ophthalmology hospital directly under the National Health Commission of China. It is China's only WHO Collaborating Centre for Eye Health and Vision and the only headquarters of international medical academic organizations in China (Asia-Pacific Academy of Ophthalmology and the Asian Office of the Asian-African Academy of Ophthalmology). For many consecutive years, the center has ranked first in ophthalmology among Chinese hospital specialty reputation rankings and has also ranked first in ophthalmology among Chinese hospital science and technology influence rankings. Furthermore, it is among the top ophthalmology institutions globally according to the Nature Index.

Year Founded: 1965
Beds: 320

Leading Specialists

Trusted Expertise Across Leading Specialties

Liu Yunsong

Professor and Vice Dean, specializing in prosthodontics and digital diagnosis and treatment

ENT

Research areas: Clinical, teaching and research in prosthodontics, digital restoration, and implant restoration. Cutting-edge technology: Has long been engaged in clinical, teaching, and research work in prosthodontics. Has led 15 national and provincial-level research projects as principal investigator, published over 0 papers as first/corresponding author, including 2 ESI highly cited papers, and was consecutively listed among the top 2% of scientists globally in 2023 and 2024. Has obtained over 30 nati

Affiliated Hospital National Center for Stomatology, Peking University School of Stomatology

Xu Gezhi

Chief Physician, Professor, Doctoral Supervisor, Former Director of Ophthalmology

ENT

-Research areas : vitreoretinal diseases, complex fundus surgery, severe ocular trauma; - Areas of expertise: 3D-navigated complex vitreoretinal surgery, repair of macular holes/recurrent retinal detachment; - Areas of expertise: Complex retinal detachment, proliferative diabetic retinopathy, high myopia macular degeneration, severe ocular rupture injury; - Academic Highlights & Core Values: Top domestic fundus surgeon, has completed numerous failed recurrent retinal detachment surgeries at other hospital

Affiliated Hospital Eye, Ear, Nose and Throat Hospital Affiliated to Fudan University (Shanghai ENT Hospital)

Zhuo Yehong

Professor, Chief Physician, Doctoral Supervisor, and Leader of Glaucoma Department

ENT

-Research areas : Glaucoma optic nerve protection, hereditary glaucoma, and surgery for refractory glaucoma. - Cutting-edge technology: Glaucoma drainage valve/drainage pin implantation, comprehensive optic nerve protection program for advanced glaucoma. - Areas of expertise: Primary angle-closure/open-angle glaucoma, refractory glaucoma with multiple postoperative relapses, and congenital glaucoma. - Academic Highlights: Led the compilation of the Chinese expert consensus on glaucoma diagnosis and treatm

Affiliated Hospital Zhongshan Ophthalmic Center, Sun Yat-sen University

Yi Hongliang

Chief Physician, Doctoral Supervisor

ENT

Research areas : obstructive sleep apnea, pharyngeal and head and neck tumors; Cutting-edge technology: Bimaxillary advancement (MMA) surgery for severe OSA; Areas of expertise: Severe snoring, pharyngeal tumors, pediatric snoring; Academic highlights: Leading expert in snoring surgery in China; Core value: Promoting precise OSA obstruction plane assessment to improve the surgical efficacy of severe snoring. Zhang Zhichang Associate Chief Physician, Doctoral Supervisor Research areas : Sacral and deep pel

Affiliated Hospital Shanghai Jiao Tong University School of Medicine Affiliated Sixth People's Hospital

Liu Yizhi

Representative of the discipline's founders, Level 2 Professor, Chief Physician, Doctoral Supervisor

ENT

-Research areas : ocular stem cells and lens regeneration; pathogenesis and treatment of cataracts. - Cutting-edge technology: Twisting-mode phacoemulsification cataract surgery, bimanual micro-incision phacoemulsification. Human lens regeneration (a major global medical breakthrough in 201). - Areas of expertise: Congenital cataracts, traumatic cataracts, complex cataracts complicated with glaucoma/uveitis, and lens diseases. - Academic Highlights: Executive Director of the Asia-Pacific Academy of Ophtha

Affiliated Hospital Zhongshan Ophthalmic Center, Sun Yat-sen University

Feng Guodong

Chief Physician, Professor, Doctoral Supervisor, Deputy Director of Department, Leading Person in Otolaryngology

ENT

-Research areas : Middle ear diseases, lateral skull base diseases, comprehensive diagnosis and treatment of tinnitus; - Areas of expertise: Cochlear implantation, ossicular chain reconstruction, and lateral skull base surgery; - Areas of expertise: Chronic otitis media, cholesteatoma, lateral skull base tumors, refractory tinnitus; - Academic Highlights & Core Values: Experts in promoting ear microsurgery techniques, focusing on multimodal comprehensive assessment of tinnitus and establishing individuali

Affiliated Hospital Peking Union Medical College Hospital, Chinese Academy of Medical Sciences

Patient Stories

See the Next Step Through Patient Journeys

Skeletal Class III Malocclusion - Reshaping Your Smile and Restarting a Confident Life

CASE 01

PATIENT JOURNEY

Skeletal Class III Malocclusion - Reshaping Your Smile and Restarting a Confident Life

ENTCosmetic Surgery

Patient records Name: Nguyen Thi Lan Age: 22 years old Nationality: Vietnamese Diagnosis: Skeletal Class III malocclusion (underbite) Treatment Hospital: Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine (Shanghai) Lan, a 22-year-old university student from Hanoi, Vietnam, is about to graduate. Despite her excellent grades, she suffers from severe underbite, which prevents her from smiling confidently and even affects her chewing and pronunciation. She dreams

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Cholesteatoma Otitis Media - Navigating the Fog and Regaining a New Voice Patient records

CASE 02

PATIENT JOURNEY

Cholesteatoma Otitis Media - Navigating the Fog and Regaining a New Voice Patient records

ENT

Patient records Name: Budi Santoso Age: 45 Nationality: Indonesia Diagnosis: Cholesteatoma-type otitis media (involving the ossicular chain) Treatment Hospital: Eye, Ear, Nose and Throat Hospital Affiliated to Fudan University (Shanghai) Budi, a 45-year-old high school music teacher from Jakarta, Indonesia, had been suffering from recurring ear discharge and hearing loss for nearly a year. Worse still, he began to lose his ability to distinguish pitch, a devastating blow to his career. Local doctors diagn

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Rhegmatogenous retinal detachment (macular involvement) - Redrawing light on a micrometer scale

CASE 03

PATIENT JOURNEY

Rhegmatogenous retinal detachment (macular involvement) - Redrawing light on a micrometer scale

ENT

Patient records Name: Arif bin Ismail Age: 58 Nationality: Malaysia Diagnosis: Rhegmatogenous retinal detachment (macular involvement) Treatment Hospital: Zhongshan Ophthalmic Center, Sun Yat-sen University (Guangzhou) Arif, 58, from Kuala Lumpur, Malaysia, is a watch repairer. His world consists of intricate gears and delicate hairsprings, requiring exceptional vision. However, a week ago, a fixed black shadow suddenly appeared in his right eye's field of vision, like a giant curtain obscuring half the s

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Nasal polypsTreatment in China

Nasal polyps Treatment in China

Recommended Hospitals

Peking Union Medical College Hospital, Chinese Academy of Medical Sciences

National Center for Stomatology, Peking University School of Stomatology

Eye, Ear, Nose and Throat Hospital Affiliated to Fudan University (Shanghai ENT Hospital)

Shanghai Jiao Tong University School of Medicine Affiliated Sixth People's Hospital

Shanghai Jiao Tong University School of Medicine Affiliated Ninth People's Hospital

Zhongshan Ophthalmic Center, Sun Yat-sen University

Trusted Expertise Across Leading Specialties

See the Next Step Through Patient Journeys

Skeletal Class III Malocclusion - Reshaping Your Smile and Restarting a Confident Life

Cholesteatoma Otitis Media - Navigating the Fog and Regaining a New Voice Patient records

Rhegmatogenous retinal detachment (macular involvement) - Redrawing light on a micrometer scale

A clear, coordinated process for efficient cross-border care

Pre-Visit Services

Remote Consultations

Travel Arrangements

Comprehensive Support in China

Post-Visit Services

Get a Care Planand Cost Estimate.

Get a Care Plan and Estimate

Nasal polyps
Treatment in China

Get a Care Plan
and Cost Estimate.