Medical Care in China

buccal mucosal cancer
Treatment in China

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Precision ENT diagnosis and treatmentcovers diseases of the nose, ears, throat and head and neck.
Comprehensive ophthalmological treatmentcovers cataracts, glaucoma, and retinal diseases, etc.
Comprehensive oral restorationcovers implants, prosthodontics, and maxillofacial diseases.
Functional reconstruction supportsthe recovery of hearing, vision, and chewing functions.

Condition Guide

About buccal mucosal cancer

Understand the condition, common triggers and treatment options that may require specialist assessment.

Disease Introduction

buccal mucosal carcinoma is a type of squamous cell carcinoma of the buccal mucosa. Precancerous lesions such as areca nut, tobacco and alcohol, and oral lichen planus are high-risk factors. Symptoms include long-term ulceration, mass, and limited mouth opening of the buccal mucosa. The tumor can infiltrate the buccal muscle and jawbone, and metastasize to the cervical lymph nodes.


Cutting-edge high-precision diagnostic and treatment technologies

1. Wide excision of buccal mucosal carcinoma : Completely remove the tumor lesion in the buccal region while ensuring safe resection margins. The resection layers are determined according to the depth and extent of tumor invasion, taking into account both radical tumor removal and preservation of buccal opening function, reducing postoperative complications such as limited mouth opening. The resection margins need to be confirmed by intraoperative pathology. Postoperative follow-up examinations are required to evaluate the efficacy and safety.
2. Microsurgical flap repair of cheek defects : When a hole or large area of soft tissue defect is formed after cheek excision, free flaps from the forearm, anterolateral thigh, etc. are used to repair the defect by anastomosing blood vessels under a microscope, reconstructing the oral cavity lining and cheek shape, restoring mouth opening and eating function, and improving postoperative appearance.
3. Functional neck dissection : Selective functional neck dissection is performed according to the risk of neck lymph node metastasis. This approach treats potential metastatic lesions while preserving important blood vessels and nerves in the neck, reducing postoperative neck functional impairment and appearance changes, lowering the risk of postoperative regional lymph node recurrence, and protecting important neck functions.
4. Intensity-modulated radiotherapy (IMRT ): IRT is used as an adjuvant therapy after surgery or for inoperable cases. It precisely covers the tumor bed, protects surrounding normal tissues, reduces local recurrence rate and radiation damage to adjacent organs, and improves the quality of life after treatment. Regular follow-up examinations are required after surgery to assess the efficacy and safety.
5. Targeted immunotherapy : For recurrent and metastatic buccal squamous cell carcinoma, the basic regimen is PD-1 immune checkpoint inhibitors combined with chemotherapy. When necessary, targeted drugs can be added to control disease progression and prolong patient survival, providing a new option for systemic treatment for advanced patients and extending their survival time.
6. Mouth opening function rehabilitation : Early postoperative systematic mouth opening training and maxillofacial rehabilitation are carried out to prevent and improve mouth opening restriction caused by scar contracture, restore normal mouth opening, eating and speech functions, and reduce postoperative facial and functional damage. Regular follow-up examinations are required after surgery to evaluate the efficacy and safety.
7. Multidisciplinary Team Assessment (MDT) : A multidisciplinary team comprehensively assesses whether the tumor has invaded the buccinator muscle, jawbone, and facial skin. Based on this, the extent of resection and repair methods are determined, and an individualized comprehensive treatment plan that balances radical cure and aesthetics is developed to avoid undertreatment or overtreatment and improve overall efficacy.

Care Overview

buccal mucosal cancer Treatment in China

The medical team will develop a personalized protocol based on the pathology type, stage, genetic test, previous treatment history, and the patient's physical condition.

Leading Specialists

Trusted Expertise Across Leading Specialties

Liu Yunsong

Professor and Vice Dean, specializing in prosthodontics and digital diagnosis and treatment

ENT

Research areas: Clinical, teaching and research in prosthodontics, digital restoration, and implant restoration. Cutting-edge technology: Has long been engaged in clinical, teaching, and research work in prosthodontics. Has led 15 national and provincial-level research projects as principal investigator, published over 0 papers as first/corresponding author, including 2 ESI highly cited papers, and was consecutively listed among the top 2% of scientists globally in 2023 and 2024. Has obtained over 30 nati

National Center for Stomatology, Peking University School of Stomatology logo Affiliated Hospital National Center for Stomatology, Peking University School of Stomatology
Xu Gezhi

Chief Physician, Professor, Doctoral Supervisor, Former Director of Ophthalmology

ENT

-Research areas : vitreoretinal diseases, complex fundus surgery, severe ocular trauma; - Areas of expertise: 3D-navigated complex vitreoretinal surgery, repair of macular holes/recurrent retinal detachment; - Areas of expertise: Complex retinal detachment, proliferative diabetic retinopathy, high myopia macular degeneration, severe ocular rupture injury; - Academic Highlights & Core Values: Top domestic fundus surgeon, has completed numerous failed recurrent retinal detachment surgeries at other hospital

Eye, Ear, Nose and Throat Hospital Affiliated to Fudan University (Shanghai ENT Hospital) logo Affiliated Hospital Eye, Ear, Nose and Throat Hospital Affiliated to Fudan University (Shanghai ENT Hospital)
Zhuo Yehong

Professor, Chief Physician, Doctoral Supervisor, and Leader of Glaucoma Department

ENT

-Research areas : Glaucoma optic nerve protection, hereditary glaucoma, and surgery for refractory glaucoma. - Cutting-edge technology: Glaucoma drainage valve/drainage pin implantation, comprehensive optic nerve protection program for advanced glaucoma. - Areas of expertise: Primary angle-closure/open-angle glaucoma, refractory glaucoma with multiple postoperative relapses, and congenital glaucoma. - Academic Highlights: Led the compilation of the Chinese expert consensus on glaucoma diagnosis and treatm

Zhongshan Ophthalmic Center, Sun Yat-sen University logo Affiliated Hospital Zhongshan Ophthalmic Center, Sun Yat-sen University
Yi Hongliang

Chief Physician, Doctoral Supervisor

ENT

Research areas : obstructive sleep apnea, pharyngeal and head and neck tumors; Cutting-edge technology: Bimaxillary advancement (MMA) surgery for severe OSA; Areas of expertise: Severe snoring, pharyngeal tumors, pediatric snoring; Academic highlights: Leading expert in snoring surgery in China; Core value: Promoting precise OSA obstruction plane assessment to improve the surgical efficacy of severe snoring. Zhang Zhichang Associate Chief Physician, Doctoral Supervisor Research areas : Sacral and deep pel

Shanghai Jiao Tong University School of Medicine Affiliated Sixth People's Hospital logo Affiliated Hospital Shanghai Jiao Tong University School of Medicine Affiliated Sixth People's Hospital
Liu Yizhi

Representative of the discipline's founders, Level 2 Professor, Chief Physician, Doctoral Supervisor

ENT

-Research areas : ocular stem cells and lens regeneration; pathogenesis and treatment of cataracts. - Cutting-edge technology: Twisting-mode phacoemulsification cataract surgery, bimanual micro-incision phacoemulsification. Human lens regeneration (a major global medical breakthrough in 201). - Areas of expertise: Congenital cataracts, traumatic cataracts, complex cataracts complicated with glaucoma/uveitis, and lens diseases. - Academic Highlights: Executive Director of the Asia-Pacific Academy of Ophtha

Zhongshan Ophthalmic Center, Sun Yat-sen University logo Affiliated Hospital Zhongshan Ophthalmic Center, Sun Yat-sen University
Feng Guodong

Chief Physician, Professor, Doctoral Supervisor, Deputy Director of Department, Leading Person in Otolaryngology

ENT

-Research areas : Middle ear diseases, lateral skull base diseases, comprehensive diagnosis and treatment of tinnitus; - Areas of expertise: Cochlear implantation, ossicular chain reconstruction, and lateral skull base surgery; - Areas of expertise: Chronic otitis media, cholesteatoma, lateral skull base tumors, refractory tinnitus; - Academic Highlights & Core Values: Experts in promoting ear microsurgery techniques, focusing on multimodal comprehensive assessment of tinnitus and establishing individuali

Peking Union Medical College Hospital, Chinese Academy of Medical Sciences logo Affiliated Hospital Peking Union Medical College Hospital, Chinese Academy of Medical Sciences

Patient Stories

See the Next Step Through Patient Journeys

Skeletal Class III Malocclusion - Reshaping Your Smile and Restarting a Confident Life CASE 01
PATIENT JOURNEY

Skeletal Class III Malocclusion - Reshaping Your Smile and Restarting a Confident Life

ENTCosmetic Surgery

Patient records Name: Nguyen Thi Lan Age: 22 years old Nationality: Vietnamese Diagnosis: Skeletal Class III malocclusion (underbite) Treatment Hospital: Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine (Shanghai) Lan, a 22-year-old university student from Hanoi, Vietnam, is about to graduate. Despite her excellent grades, she suffers from severe underbite, which prevents her from smiling confidently and even affects her chewing and pronunciation. She dreams

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Cholesteatoma Otitis Media - Navigating the Fog and Regaining a New Voice Patient records CASE 02
PATIENT JOURNEY

Cholesteatoma Otitis Media - Navigating the Fog and Regaining a New Voice Patient records

ENT

Patient records Name: Budi Santoso Age: 45 Nationality: Indonesia Diagnosis: Cholesteatoma-type otitis media (involving the ossicular chain) Treatment Hospital: Eye, Ear, Nose and Throat Hospital Affiliated to Fudan University (Shanghai) Budi, a 45-year-old high school music teacher from Jakarta, Indonesia, had been suffering from recurring ear discharge and hearing loss for nearly a year. Worse still, he began to lose his ability to distinguish pitch, a devastating blow to his career. Local doctors diagn

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Rhegmatogenous retinal detachment (macular involvement) - Redrawing light on a micrometer scale CASE 03
PATIENT JOURNEY

Rhegmatogenous retinal detachment (macular involvement) - Redrawing light on a micrometer scale

ENT

Patient records Name: Arif bin Ismail Age: 58 Nationality: Malaysia Diagnosis: Rhegmatogenous retinal detachment (macular involvement) Treatment Hospital: Zhongshan Ophthalmic Center, Sun Yat-sen University (Guangzhou) Arif, 58, from Kuala Lumpur, Malaysia, is a watch repairer. His world consists of intricate gears and delicate hairsprings, requiring exceptional vision. However, a week ago, a fixed black shadow suddenly appeared in his right eye's field of vision, like a giant curtain obscuring half the s

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