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Medical Care in China

Multiple organ transplantation
Treatment in China

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Multi-organ transplantationcovers liver, kidney, lung, heart, and combined transplants.

Complex case assessmentprovides a comprehensive evaluation for end-stage and complex organ diseases.

Pediatric transplant supportcovers some complex cases such as pediatric living donor liver transplantation.

Postoperative long-term managementfocuses on rejection, infection, and transplant organ function.

Condition Guide

About Multiple organ transplantation

Understand the condition, common triggers and treatment options that may require specialist assessment.

Disease Introduction

Introduction : Multi-organ transplantation (multi-organ transplantation/organ cluster transplantation) refers to the simultaneous or sequential transplantation of two or more anatomically and functionally related end-stage organs. It is divided into abdominal organ cluster transplantation (liver, pancreas, duodenum/liver, pancreas, kidney) and thoracic multi-organ transplantation (heart and liver, heart and lung, heart and kidney). It is the most difficult surgical procedure in the field of organ transplantation and can only be performed by top transplant centers in China. It is used for patients with single organ failure combined with irreversible decompensation of multiple organ functions.
Core symptoms : Primary disease drives sequential failure of multiple organs: liver failure with jaundice, coagulation disorders, portal hypertension and upper gastrointestinal bleeding; renal failure with uremia, increased volume overload, and metabolic acidosis; pancreatic failure with refractory glucose metabolism disorder; heart failure with circulatory instability; small bowel failure with severe malnutrition and parenteral nutrition dependence; may be complicated by multiple systemic internal environment disorders, recurrent catheter infections, and coagulation breakdown.
Pathological mechanism : (1) The primary disease causes irreversible structural damage to the target organ. Single organ failure induces a chain of secondary organ damage through hemodynamic, metabolic, endocrine and immune pathways, forming a vicious cycle of multi-organ interactive failure. (2) End-stage organs have fibrosis, vascular bed damage, and persistent tissue insufficiency, and homeostasis cannot be maintained in the long term through support means such as dialysis and artificial organs; (3) Transplantation level: Grafts contain a large number of immune-active cells (especially in the small intestine), which poses a dual risk of host rejection and graft-versus-host disease; the immune interaction effect of multi-organ grafts can induce immune tolerance to a certain extent, but the risk of infection, thrombosis and anastomotic complications is significantly higher than that of single organ transplantation.

Cutting-edge high-precision diagnostic and treatment technologies

Simplified upper abdominal multi-organ cluster transplantation technique: Improved whole organ harvesting and reconstruction, without blocking the abdominal aorta for reconstruction and the portal vein for reconstruction, reducing the scope of abdominal dissection, reducing intraoperative bleeding, intestinal leakage, and biliary complications. It is the first of its kind in China and has the largest case system in the world.
Ischemia-free organ transplantation technology system: The donor organ is continuously perfused physiologically outside the body, avoiding cold ischemia-reperfusion injury, reducing the risk of primary nonfunctional grafts, and can be combined with multi-organ donor joint repair, adapting to the acquisition of multi-organ grafts.
ECMO/Extracorporeal Circulation Assisted Multi-Organ Transplantation: Dynamic hemodynamic support during heart-liver and heart-lung transplantation, real-time temperature and anticoagulation regulation, solving the problem of circulatory fluctuations in transthoracic-peritoneal transplantation.
Whole organ repair technology: multi-organ donor repair in one session, prefabrication and reconstruction of blood vessels, bile ducts and digestive tract, shortening the cold ischemia time of donor organs.
Perioperative multimodal real-time monitoring technology: intraoperative transesophageal ultrasound, continuous hemodynamic monitoring, graft perfusion assessment, bedside immune monitoring, and early warning system for microorganisms.

Care Overview

Multiple organ transplantation Treatment in China

The medical team will develop a personalized protocol based on the pathology type, stage, genetic test, previous treatment history, and the patient's physical condition.

1. Core treatment logic : Strict screening of indications and contraindications → Multidisciplinary team (MDT) full-cycle assessment and deduction → HLA typing of donors and recipients and organ quality assessment → Individualized surgical timing planning → Triple control of intraoperative blood flow/coagulation/infection → Refined management of postoperative immune tolerance → Long-term multi-system follow-up.
2. Core principles: Multiple organ failure is a cause-and-effect relationship, and a single simultaneous transplant can break the vicious cycle of multiple organ failure in one go; relying on the immune interaction between multiple organs, the risk of rejection and infection is balanced, and the trauma of multiple single organ transplants is avoided.
3. Treatment plan : ① Preoperative MDT comprehensive assessment plan: joint assessment by transplant surgery, critical care, anesthesia, nephrology, cardiology, endocrinology, infection, imaging and nutrition to predict the risk of intraoperative adhesion, bleeding and circulatory collapse, complete surgical simulation and deduction, screen recipients who can tolerate transplantation, and exclude absolute contraindications such as tumors and active infections.
② Integrated organ acquisition and preparation scheme: multiple organs are harvested from the same donor, and the reconstruction and prefabrication of blood vessels, bile ducts and digestive tract are completed simultaneously. The organ preservation and perfusion strategy is optimized to minimize the duration of cold ischemia in multiple organs.
③Simultaneous combined transplantation surgical approach: Select the implantation sequence of thoracic/abdominal organs according to organ anatomical divisions, and prioritize stabilizing the core circulatory organs; adopt modified vascular reconstruction and digestive tract reconstruction techniques to reduce anastomotic complications.
④ Perioperative hemodynamics and coagulation regulation: on-demand extracorporeal life support, dynamic volume management, goal-oriented coagulation protection, and avoidance of intraoperative massive hemorrhage and graft vascular thrombosis.
⑤ Tiered immune management program: Based on the characteristics of immune interaction in multi-organ grafts, individualized immune monitoring, dynamic assessment of rejection risk, balancing of immunosuppression intensity, and reduction of the dual risks of infection and rejection.
⑥ Postoperative multi-system long-term follow-up plan: regular monitoring of multi-organ function, graft morphology, immune status, and infectious pathogens; integrated intervention of nutrition and rehabilitation; and early screening for long-term complications.

1. Advantage of radical cure: A single surgery can replace multiple failing organs simultaneously, breaking the pathological loop of mutual damage between organs, which is different from palliative solutions such as dialysis and artificial organs that can only provide temporary support.
2. Immunobiological advantages: Homologous multi-organ grafts have immune interaction effects, which can induce immune tolerance to a certain extent. The risk of rejection in some recipients is lower than that of transplantation of highly immunogenic organs such as single small intestine.
3. Surgical trauma advantages: Simplified organ cluster technology avoids repeated surgical trauma and abdominal/thoracic adhesions caused by multiple organ transplants, and reduces the cumulative mortality rate of multiple surgeries.
4. Long-term survival benefits: The 1-year and 5-year survival rates of multi-organ transplantation at top domestic centers have reached international leading levels. Most recipients can be weaned off dialysis, parenteral nutrition, and insulin replacement, and restore their autonomous organ function and quality of life.
5. Advantages of full-chain management: MDT (Multidisciplinary Team) integrates preoperative assessment, intraoperative life support, intensive care, and long-term multi-organ follow-up, and has a significantly stronger ability to deal with complex complications of multiple systems than a single specialty.

Network of partner hospitals

Recommended Hospitals

Selected leading medical centers with strong specialties and international patient services.

Peking Union Medical College Hospital, Chinese Academy of Medical Sciences

Beijing · Partner Hospital

Peking Union Medical College Hospital, Chinese Academy of Medical Sciences

RehabilitationOrgan TransplantRare & Complex DiseasesOncologyGastroenterologyNeurologyUrologyInternal MedicineSurgeryHepatobiliaryOrthopedicsObstetrics & GynecologyENTCosmetic Surgery

In the ranking of Chinese hospitals released by the Fudan University Hospital Management Institute, Peking Union Medical College Hospital has topped the comprehensive ranking for more than ten consecutive years, and has twice ranked first in the national performance evaluation of tertiary public hospitals. Among the 42 specialties covered in the comprehensive specialty ranking, 28 of Peking Union Medical College Hospital's specialties are ranked in the top 10. Nine specialties, including pathology, rheumatology, obstetrics and gynecology, general surgery, neurology, nuclear medicine, emergency medicine, critical care medicine, and allergy, rank first in the country; several specialties, including radiology, anesthesiology, endocrinology, laboratory medicine, ultrasound medicine, and gastroenterology, rank second in the country. The hospital is a national center for the diagnosis and treatment of complex, critical, and rare diseases designated by the National Health Commission, a national demonstration base for higher medical education and standardized residency training, and a national core base for clinical medical research and technological innovation.

Year Founded: 1921
Beds: 3000

Fuwai Hospital, Chinese Academy of Medical Sciences

Beijing · Partner Hospital

Fuwai Hospital, Chinese Academy of Medical Sciences

Organ TransplantCardio-Cerebrovascular

The hospital is home to the National Center for Cardiovascular Diseases and is a national-level tertiary-grade Class A cardiovascular disease specialist hospital. It has consistently ranked first in the nation for cardiovascular disease in the Fudan University specialist rankings for many years. The hospital houses national-level platforms such as the National Key Laboratory of Cardiovascular Diseases and the National Clinical Research Center for Cardiovascular Diseases, and was among the first batch of national medical centers to receive national support. In 2011, it performed over 10,000 internal and surgical procedures, becoming the world's largest heart disease treatment center. For 13 consecutive years, the 30-day mortality rate for cardiac surgery has remained below 1%, maintaining an internationally leading level.

Year Founded: 1956
Beds: 1300

Beijing Friendship Hospital (Second Clinical Medical College), Capital Medical University

Beijing · Partner Hospital

Beijing Friendship Hospital (Second Clinical Medical College), Capital Medical University

RehabilitationOrgan TransplantGastroenterologyInternal MedicineSurgery

The hospital is the supporting unit of the National Clinical Research Center for Digestive Diseases and the National Key Laboratory of Digestive Health, and a pilot unit of the National Flagship Hospital for Integrated Traditional Chinese and Western Medicine. It has 12 national key clinical specialties, 27 doctoral programs, and 33 master's programs. It is ranked A+ in the national performance evaluation of tertiary public hospitals and is one of the earliest hospitals in the country to undertake the tasks of healthcare for cadres and medical treatment for foreign guests. In 2018, it became one of the first batch of pilot units in the country to establish a modern hospital management system.

Year Founded: 1952
Beds: 3306

Beijing · Partner Hospital

China-Japan Friendship Hospital

RehabilitationOrgan TransplantRare & Complex DiseasesInternal Medicine

China-Japan Friendship Hospital is a national center for respiratory medicine, a national center for integrated traditional Chinese and Western medicine, a national center for telemedicine and internet medicine, a national clinical research center for respiratory diseases, a national telemedicine and training center, and the supporting unit of the World Health Organization (WHO) Collaborating Centre for Smoking Cessation and Prevention of Respiratory Diseases. The hospital is a national pilot hospital for high-quality development and a national pilot hospital for clinical research. It boasts 2 National Masters of Traditional Chinese Medicine, 3 National Renowned Traditional Chinese Medicine Practitioners, 5 Qihuang Scholars, and 9 Capital National Masters of Traditional Chinese Medicine. In the fields of intractable diseases, critical illnesses, and rare diseases, it ranks 5th nationwide according to the Fudan University rankings.

Year Founded: 1984
Beds: 400

Huashan Hospital Affiliated to Fudan University

Shanghai · Partner Hospital

Huashan Hospital Affiliated to Fudan University

RehabilitationOrgan TransplantRare & Complex DiseasesNeurologyInternal MedicineOrthopedicsDermatology

The hospital is responsible for the construction of three national-level medical centers: the National Medical Center for Neurological Diseases, the National Medical Center for Infectious Diseases, and the National Clinical Research Center for Geriatric Diseases. It is also the National Quality Control Center for Skin and Sexually Transmitted Diseases (under construction). It boasts 20 national key clinical specialties designated by the Ministry of Health, 10 national key disciplines designated by the Ministry of Education, and 2 national key laboratories. Its national examination scores of A++ rank it among the top tier nationwide, making it one of the most renowned and internationally-oriented medical, educational, and research centers in China.

Year Founded: 1907
Beds: 3142

Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

Shanghai · Partner Hospital

Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

Organ TransplantGastroenterologyUrologyInternal MedicineObstetrics & Gynecology

Renji Hospital boasts 13 national key clinical specialties (Gastroenterology, Obstetrics, Cardiology, Neurosurgery, General Surgery, Urology, Nephrology, Imaging Medicine, Rheumatology, Allergy, Transplantation, and Critical Care Medicine), and houses the National Key Laboratory of Oncology, the Key Laboratory of Anesthesiology of the Ministry of Education, and the Key Laboratory of Gastroenterology of the National Health Commission. The hospital ranks among the top in China for several specialties in the Fudan University Hospital Rankings, with its gastroenterology program consistently ranking first in the country for many years. It is also a co-construction unit of the National Regional Medical Center for Digestive Diseases.

Year Founded: 1844
Beds: 2750

Leading Specialists

Trusted Expertise Across Leading Specialties

Lü Fanzhen

Chief Physician, Key Member of Lung Transplant Surgery Team

Organ Transplant

-Research areas : Lung transplant surgery, thoracoscopic lung transplantation; - Areas of expertise: Single/double lung transplantation surgery, perioperative critical care management after lung transplantation; - Diseases specializing in: end-stage bronchiectasis, pneumoconiosis, and late-stage lung damage from paraquat poisoning; - Academic Highlights & Core Values: Undertakes a large amount of clinical work in lung transplantation, deeply involved in optimizing the clinical process of ECMO-bridging lun

Affiliated Hospital Shanghai Pulmonary Hospital (Shanghai Pulmonary Hospital Affiliated to Tongji University)

Yang Jiayin

Chief Physician, Doctoral Supervisor, Director of Liver Transplantation Center, Director of General Surgery, Director of Organ Transplantation Center, Director of the National Health Commission Key Laboratory of Transplantation Engineering and Transplantation Immunology

Organ Transplant

-Research areas : Adult DCD liver transplantation, liver transplantation in elderly recipients, multi-organ transplantation, transplant immunology, optimization of perioperative procedures for liver transplantation; safety studies of living donor liver transplantation; quality assessment and preservation of DCD donor livers. - Cutting-edge technologies: ABO incompatible liver transplantation, liver-kidney combined transplantation, transplantation programs for elderly critically ill recipients; pioneering

Affiliated Hospital West China Hospital of Sichuan University

Yan Linan

Director of the Liver Transplant Center & Department of Liver Surgery, Professor, Doctoral Supervisor, Founder of the Discipline, First-Class Expert, Leading Figure in the Field of Liver Transplantation in my country

Organ Transplant

-Research areas : Basic and clinical aspects of liver transplantation, and the development of living donor liver transplantation technology systems. - Cutting-edge technology: A pioneer in adult living donor liver transplantation in mainland China, leading the implementation of more than 1,200 clinical liver transplants and achieving eight leading firsts in liver transplantation technology nationwide; he began performing pediatric living donor liver transplantation in 2001 and performed the first adult li

Affiliated Hospital West China Hospital of Sichuan University

Xia Lei

Chief Physician, Doctoral Supervisor, Deputy Director of Liver Surgery

Organ Transplant

-Research areas : Adult liver transplantation, complex hepatobiliary surgery, combined liver and kidney transplantation; - Areas of expertise: Dual-donor liver transplantation, combined liver and kidney transplantation, and complex hepatobiliary tumor surgery; - Areas of expertise: End-stage cirrhosis, cirrhosis complicated with renal failure, and complex hepatobiliary malignancies; - Academic Highlights & Core Values: Responsible for the clinical system of multi-organ transplantation, handling complex ad

Affiliated Hospital Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

Wan Ping

Associate Chief Physician, Liver Surgery Expert at Renji Hospital.

Organ Transplant

Research Areas : Pediatric liver transplantation, Kasai procedure for biliary atresia, and complex liver tumor resection, among other pediatric liver surgeries. Cutting-Edge Techniques: Proficient in the surgical treatment of pediatric liver diseases such as biliary atresia, inherited metabolic diseases, cholestasis, and hepatoblastoma, having treated over 1700 cases of various pediatric liver diseases and rare diseases; as a core member of the team, systematically conducting liver transplantation surgery

Affiliated Hospital Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

Zhan Qingyuan

Chief Physician, Professor, Head of Respiratory Critical Care and ECMO

Organ Transplant

Research areas : perioperative extracorporeal life support during transplantation, ARDS, and post-transplant severe respiratory failure; Cutting-edge technologies: ECMO bridging lung transplantation and treatment of severe respiratory complications after transplantation; Areas of expertise: critical respiratory failure before lung transplantation and primary graft failure after transplantation; Academic highlights: Leading expert in domestic ECMO guidelines; Core value: Establishing standardized treatment

Affiliated Hospital China-Japan Friendship Hospital

Patient Stories

See the Next Step Through Patient Journeys

CASE 01

PATIENT JOURNEY

Restarting the "Life Purifier"—An Indonesian Youth's Kidney Miracle Patient records

Organ Transplant

Patient records Name: Adi Age: 28 Nationality: Indonesia Diagnosis: End-stage renal disease (IgA nephropathy) Treatment Hospital: Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology (Wuhan) Freed from the constraints of the dialysis machine, we found him a "matching" new life. Adi, a talented young photographer from Bandung, Indonesia, 28, had captured countless moving moments with his lens. Five years ago, however, he developed gross hematuria after a cold

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CASE 02

PATIENT JOURNEY

Breaking Free from the "Shackles of Breathing"—A Thai Elder's Heartfelt Words Continued in China

Organ Transplant

Patient records Name: Somchai Age: 65 Nationality: Thailand Diagnosis: End-stage idiopathic pulmonary fibrosis (IPF) Treatment Hospital: China-Japan Friendship Hospital (National Center for Respiratory Medicine) When breathing becomes a luxury, we find him a "new leaf" of life. Somchai, a 65-year-old retired university professor from Chiang Mai, Thailand, was a gentle and refined man. However, at a time when he should have been enjoying his retirement, an "invisible shackle" choked him. He suffered from i

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Heart Transplant: A Transnational Relay of a

CASE 03

PATIENT JOURNEY

Heart Transplant: A Transnational Relay of a "Chinese Heart"—An UAE Patient Finds a Solution for End-Stage Heart Failure in China

Organ Transplant

Patient records Name: Ahmed (pseudonym) Age: 38 Nationality: Dubai, United Arab Emirates Diagnosis: Dilated cardiomyopathy, end-stage heart failure, post-cardiac resynchronization therapy (CRT-D) Treatment Hospital: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology Heart transplantation is the last hope for patients with end-stage heart failure. But when this "heart of hope" needs to be found across borders, patients face not only the complex rules of organ allocation,

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Pediatric Living Donor Liver Transplant: When

CASE 04

PATIENT JOURNEY

Pediatric Living Donor Liver Transplant: When "Not Living Past One Year Old" Becomes a Prophecy—A Mongolian Mother's Journey of "Saving Her Son by Donating Part of Her Liver"

Organ TransplantHepatobiliaryPediatrics

Patient records Name: Batbayar (pseudonym) Age: 11 months Nationality: Ulaanbaatar, Mongolia Diagnosis: Congenital biliary atresia, decompensated biliary cirrhosis after Kasai procedure. Treatment Hospital: Beijing Friendship Hospital, Capital Medical University Pediatric living donor liver transplantation is the crown jewel of organ transplantation. It tests not only surgical skills but also a healthcare system's comprehensive capabilities in donor safety, postoperative management, and long-term follow-u

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Service Process

A clear, coordinated process for efficient cross-border care

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Remote Consultations
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Comprehensive Support in China
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05
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We assist with notarisation of medical expense documents, airport drop-off, organisation and translation of medical records, remote rehabilitation guidance, and coordination of international referrals.

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Multiple organ transplantationTreatment in China

Multiple organ transplantation Treatment in China

Recommended Hospitals

Peking Union Medical College Hospital, Chinese Academy of Medical Sciences

Fuwai Hospital, Chinese Academy of Medical Sciences

Beijing Friendship Hospital (Second Clinical Medical College), Capital Medical University

China-Japan Friendship Hospital

Huashan Hospital Affiliated to Fudan University

Renji Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

Shanghai Pulmonary Hospital (Shanghai Pulmonary Hospital Affiliated to Tongji University)

Southern Medical University Southern Hospital

West China Hospital of Sichuan University

Trusted Expertise Across Leading Specialties

See the Next Step Through Patient Journeys

Restarting the "Life Purifier"—An Indonesian Youth's Kidney Miracle Patient records

Breaking Free from the "Shackles of Breathing"—A Thai Elder's Heartfelt Words Continued in China

Heart Transplant: A Transnational Relay of a "Chinese Heart"—An UAE Patient Finds a Solution for End-Stage Heart Failure in China

Pediatric Living Donor Liver Transplant: When "Not Living Past One Year Old" Becomes a Prophecy—A Mongolian Mother's Journey of "Saving Her Son by Donating Part of Her Liver"

Living Donor Liver Transplantation: When Life Counts Down in Waiting—How a Russian Engineer Finds the Answer to "Living Donor Liver Transplantation" in China

A clear, coordinated process for efficient cross-border care

Pre-Visit Services

Remote Consultations

Travel Arrangements

Comprehensive Support in China

Post-Visit Services

Get a Care Planand Cost Estimate.

Get a Care Plan and Estimate

Multiple organ transplantation
Treatment in China

Get a Care Plan
and Cost Estimate.