Medical Care in China

Pituitary tumors (prolactinoma, growth hormone-secreting tumor, Cushing's disease, etc.)
Treatment in China

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Multidisciplinary diagnosis and treatmentwith collaboration among oncology, surgery, and related specialties to develop treatment plans.
The comprehensive treatment systemcovers surgery, radiotherapy, chemotherapy, targeted therapy, and immunotherapy.
Proton and heavy ion therapy selectionis used for precise radiotherapy assessment for certain indications.
Personalized treatmentplans are developed based on pathology, staging, and molecular characteristics.

Condition Guide

About Pituitary tumors (prolactinoma, growth hormone-secreting tumor, Cushing's disease, etc.)

Understand the condition, common triggers and treatment options that may require specialist assessment.

Disease Introduction

Pituitary tumors are common benign tumors located on the pituitary gland, the endocrine center at the base of the skull. They are often discovered due to the secretion of abnormal hormones or compression of the optic nerve. Women often present with menstrual disorders and galactorrhea, while adults may experience enlarged hands and feet, a widened face (acromegaly), a moon face, and central obesity (Cushing's disease). When the tumor enlarges and compresses the optic chiasm, it can cause bitemporal visual field defects, decreased vision, and even headaches.

Cutting-edge high-precision diagnostic and treatment technologies

  1. Endoscopic transsphenoidal minimally invasive surgery : The tumor can be removed directly through the natural nasal cavity to the pituitary fossa without craniotomy. With the assistance of neuronavigation and real-time imaging such as intraoperative MRI, the complete tumor resection rate can reach more than 80%.
  2. Long-acting paretide approved : Paretide microspheres for injection (Xenifene) were approved by the National Medical Products Administration in April 2025 as a second-generation somatostatin analog for the treatment of acromegaly in adults who are not candidates for surgery or whose acromegaly is poorly controlled by first-generation drugs.
  3. Cushing's new oral drug : Ozolstat phosphate tablets were approved by the National Medical Products Administration in September 2024 and launched in China in April 2025. As an oral cortisol synthesis inhibitor for adult Cushing's syndrome, it can rapidly and persistently reduce cortisol.
  4. Stereotactic radiotherapy : For postoperative residual, recurrent, or invasive tumors adjacent to the optic nerve, stereotactic radiosurgery such as Gamma Knife and CyberKnife, as well as fractionated intensity-modulated radiotherapy, are used. If necessary, proton beam therapy is performed to reduce toxicity to the visual pathway and surrounding structures.
  5. Temozolomide treatment : For invasive pituitary adenomas and pituitary cancers that are resistant to surgery, radiotherapy, and drug treatment, the European Endocrine Society guidelines recommend alkylating agents like temozolomide as first-line chemotherapy. Targeted therapy and peptide receptor radionuclide therapy are directions for further exploration.

Care Overview

Pituitary tumors (prolactinoma, growth hormone-secreting tumor, Cushing's disease, etc.) Treatment in China

The medical team will develop a personalized protocol based on the pathology type, stage, genetic test, previous treatment history, and the patient's physical condition.

Leading Specialists

Trusted Expertise Across Leading Specialties

Liu Zhuowei

Deputy Director of the Center, specializing in minimally invasive robotic surgery for urological tumors

Oncology

Research areas: Surgical treatment of urinary tract tumors, minimally invasive treatment with robot-assisted/laparoscopic surgery, comprehensive treatment of bladder cancer and testicular cancer, and pediatric oncological surgery. Cutting-edge technologies: Pioneered domestically in modified robot-assisted/laparoscopic retroperitoneal lymph node dissection for testicular cancer and ultra-extended lymph node dissection for bladder cancer. Director of the Expert Committee of the first international training

Sun Yat-sen University Cancer Center logo Affiliated Hospital Sun Yat-sen University Cancer Center
Shi Yuankai

Professor – Specializing in the internal medicine treatment of lymphoma and lung cancer

Oncology

Research areas: Medical treatment of tumors such as lymphoma, lung cancer, head and neck cancer, and gastrointestinal cancer; anti-tumor drugs and related clinical research. Cutting-edge technology: Dedicated to the medical treatment of tumors such as lymphoma, lung cancer, head and neck cancer, and gastrointestinal cancer. Conducted over 300 clinical studies on anti-tumor drugs and related research, and led the completion of registration clinical trials for more than 10 domestically produced new drugs an

Tianjin Medical University Cancer Hospital logo Affiliated Hospital Tianjin Medical University Cancer Hospital
Xu Binghe

Academician of the Chinese Academy of Engineering, Chief Physician, Tenured Professor, Doctoral Supervisor, Director of the National Clinical Research Center for New Drugs (Anti-tumor).

Oncology

Research areas: Personalized precision treatment for breast cancer and development of new anticancer drugs; clinical, applied basic and translational research on breast cancer. Cutting-edge technologies: Established a new method for personalized breast cancer screening, significantly improving early detection rates; pioneered a new field of personalized treatment based on molecular subtyping. Led the development of 19 guidelines, including the National Health Commission's "Guidelines for Rational Drug Use

Fudan University Cancer Hospital logo Affiliated Hospital Fudan University Cancer Hospital
Cao Lu

Associate Chief Physician, Doctoral Supervisor

Oncology

-Research areas : Pediatric oncology, central nervous system tumors, proton therapy for soft tissue sarcoma. - Cutting-edge technologies: Optimization of proton dose for pediatric tumors to reduce long-term radiation damage during growth and development; stratified proton therapy for intracranial germ cell tumors and craniopharyngiomas. - Areas of expertise: intracranial tumors in children, rhabdomyosarcoma, solid tumors in adolescents, and soft tissue sarcoma in adults. - Academic Highlights: A pioneer i

Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine logo Affiliated Hospital Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Sun Ying

Professor, Chief Physician, Doctoral Supervisor, Leading Expert in Nasopharyngeal Carcinoma

Oncology

Research area : Precision radiotherapy and comprehensive treatment of nasopharyngeal carcinoma. Academic Highlights: A core expert in nasopharyngeal carcinoma at the Department of Radiation Oncology, China Cancer Hospital, who has driven multiple research findings to rewrite international clinical guidelines.

Sun Yat-sen University Cancer Center logo Affiliated Hospital Sun Yat-sen University Cancer Center
Yu Zhuo

Associate Chief Physician, Key Member of the Department of Medical Oncology

Oncology

Research areas : Comprehensive medical treatment of gastrointestinal tumors, hepatobiliary and pancreatic tumors, lung cancer, and breast cancer; Cutting-edge technologies: Targeted immunotherapy for solid tumors, management of adverse tumor reactions, and nutritional support; Areas of expertise: Gastric cancer, colorectal cancer, pancreatic cancer, and advanced solid tumors; Academic highlights: Visiting scholar at MD Anderson Cancer Center, and participation in multiple clinical trials of new anti-tumor

Tsinghua University Beijing Tsinghua Chang Gung Hospital logo Affiliated Hospital Tsinghua University Beijing Tsinghua Chang Gung Hospital

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