Medical Care in China

Intracranial skull base tumors (meningioma, acoustic neuroma, craniopharyngioma, chordoma, etc.)
Treatment in China

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Multidisciplinary diagnosis and treatmentwith collaboration among oncology, surgery, and related specialties to develop treatment plans.
The comprehensive treatment systemcovers surgery, radiotherapy, chemotherapy, targeted therapy, and immunotherapy.
Proton and heavy ion therapy selectionis used for precise radiotherapy assessment for certain indications.
Personalized treatmentplans are developed based on pathology, staging, and molecular characteristics.

Condition Guide

About Intracranial skull base tumors (meningioma, acoustic neuroma, craniopharyngioma, chordoma, etc.)

Understand the condition, common triggers and treatment options that may require specialist assessment.

Disease Introduction

Intracranial skull base tumors refer to a large category of tumors that grow in the bone of the skull base and surrounding spaces. Common types include skull base meningiomas, acoustic neuromas (vestibular schwannomas), craniopharyngiomas, chordomas, and olfactory neuroblastomas. Because they are located close to the optic nerve, brainstem, internal carotid artery, and multiple cranial nerves, early symptoms often include headache, decreased vision, facial numbness, tinnitus, and hearing loss. Due to their deep location, surgery is very difficult.

Cutting-edge high-precision diagnostic and treatment technologies

  1. Extended transnasal endoscopy : The extended transnasal neuroendoscopic approach (EEA) can directly reach the midline areas such as the sellar region and clivus through the nasal cavity, allowing for direct visualization and separation of the tumor from the normal neurovascular interface, and treatment of craniopharyngioma, chordoma, tuberculum sellae meningioma, etc.
  2. Pedicled mucosal flap reconstruction : Multi-layer skull base reconstruction based on the vascularized pedicled nasal septum mucosal flap (Hadad flap) has a large area and good blood supply, which significantly reduces the incidence of cerebrospinal fluid leakage after extended transnasal surgery and has been included in relevant expert consensus.
  3. Multimodal neurological monitoring : During surgeries such as acoustic neuroma, multimodal electrophysiological monitoring such as facial nerve electromyography, brainstem auditory evoked potentials, and motor evoked potentials are carried out simultaneously, and the monitoring stops immediately upon warning, so as to achieve real-time protection of facial and auditory nerve function.
  4. Proton and heavy ion radiotherapy : pencil beam scanning of protons and carbon ions is used to treat skull base chordoma and chondrosarcoma. Highly conformal irradiation is achieved by utilizing the Bragg peak. The local control rate of 137 patients at Shanghai Proton and Heavy Ion Center was approximately 88.1% after 2 years.
  5. Dual-scope combined minimally invasive technique : The combination of microscope and neuroendoscopy, supplemented by neuronavigation, can expose the blind spots of the microscope, fully expose complex areas such as the petroclival region and the ventral cavernous sinus, improve the complete resection rate and reduce brain traction.

Care Overview

Intracranial skull base tumors (meningioma, acoustic neuroma, craniopharyngioma, chordoma, etc.) Treatment in China

The medical team will develop a personalized protocol based on the pathology type, stage, genetic test, previous treatment history, and the patient's physical condition.

Leading Specialists

Trusted Expertise Across Leading Specialties

Liu Zhuowei

Deputy Director of the Center, specializing in minimally invasive robotic surgery for urological tumors

Oncology

Research areas: Surgical treatment of urinary tract tumors, minimally invasive treatment with robot-assisted/laparoscopic surgery, comprehensive treatment of bladder cancer and testicular cancer, and pediatric oncological surgery. Cutting-edge technologies: Pioneered domestically in modified robot-assisted/laparoscopic retroperitoneal lymph node dissection for testicular cancer and ultra-extended lymph node dissection for bladder cancer. Director of the Expert Committee of the first international training

Sun Yat-sen University Cancer Center logo Affiliated Hospital Sun Yat-sen University Cancer Center
Shi Yuankai

Professor – Specializing in the internal medicine treatment of lymphoma and lung cancer

Oncology

Research areas: Medical treatment of tumors such as lymphoma, lung cancer, head and neck cancer, and gastrointestinal cancer; anti-tumor drugs and related clinical research. Cutting-edge technology: Dedicated to the medical treatment of tumors such as lymphoma, lung cancer, head and neck cancer, and gastrointestinal cancer. Conducted over 300 clinical studies on anti-tumor drugs and related research, and led the completion of registration clinical trials for more than 10 domestically produced new drugs an

Tianjin Medical University Cancer Hospital logo Affiliated Hospital Tianjin Medical University Cancer Hospital
Xu Binghe

Academician of the Chinese Academy of Engineering, Chief Physician, Tenured Professor, Doctoral Supervisor, Director of the National Clinical Research Center for New Drugs (Anti-tumor).

Oncology

Research areas: Personalized precision treatment for breast cancer and development of new anticancer drugs; clinical, applied basic and translational research on breast cancer. Cutting-edge technologies: Established a new method for personalized breast cancer screening, significantly improving early detection rates; pioneered a new field of personalized treatment based on molecular subtyping. Led the development of 19 guidelines, including the National Health Commission's "Guidelines for Rational Drug Use

Fudan University Cancer Hospital logo Affiliated Hospital Fudan University Cancer Hospital
Cao Lu

Associate Chief Physician, Doctoral Supervisor

Oncology

-Research areas : Pediatric oncology, central nervous system tumors, proton therapy for soft tissue sarcoma. - Cutting-edge technologies: Optimization of proton dose for pediatric tumors to reduce long-term radiation damage during growth and development; stratified proton therapy for intracranial germ cell tumors and craniopharyngiomas. - Areas of expertise: intracranial tumors in children, rhabdomyosarcoma, solid tumors in adolescents, and soft tissue sarcoma in adults. - Academic Highlights: A pioneer i

Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine logo Affiliated Hospital Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Sun Ying

Professor, Chief Physician, Doctoral Supervisor, Leading Expert in Nasopharyngeal Carcinoma

Oncology

Research area : Precision radiotherapy and comprehensive treatment of nasopharyngeal carcinoma. Academic Highlights: A core expert in nasopharyngeal carcinoma at the Department of Radiation Oncology, China Cancer Hospital, who has driven multiple research findings to rewrite international clinical guidelines.

Sun Yat-sen University Cancer Center logo Affiliated Hospital Sun Yat-sen University Cancer Center
Yu Zhuo

Associate Chief Physician, Key Member of the Department of Medical Oncology

Oncology

Research areas : Comprehensive medical treatment of gastrointestinal tumors, hepatobiliary and pancreatic tumors, lung cancer, and breast cancer; Cutting-edge technologies: Targeted immunotherapy for solid tumors, management of adverse tumor reactions, and nutritional support; Areas of expertise: Gastric cancer, colorectal cancer, pancreatic cancer, and advanced solid tumors; Academic highlights: Visiting scholar at MD Anderson Cancer Center, and participation in multiple clinical trials of new anti-tumor

Tsinghua University Beijing Tsinghua Chang Gung Hospital logo Affiliated Hospital Tsinghua University Beijing Tsinghua Chang Gung Hospital

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